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Reports · October 2025

The 2025-26 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors

How the Big Three and specialty distributors make money — and what compressed margins mean for manufacturers.

Wholesaler profitability is no longer a simple buy-and-hold story. Fee-for-service contracts, specialty distribution, and manufacturer services now sit beside a thinner spread on the traditional invoice.

This is the prior edition of the wholesaler study. Ask from the sidebar about a specific wholesaler or how a launch was distributed in 2025-26.

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